| N-Acetyl-L-glutamic acid Basic information |
| Product Name: | N-Acetyl-L-glutamic acid |
| Synonyms: | acetylglutamicacid;L-Glutamic acid, N-acetyl-;l-glutamicaci;N-ALPHA-ACETYL-L-GLUTAMIC ACID;N-AC-L-GLU;N-ACETYL-L-GLU;N-ACETYL-L-GLUTAMIC ACID;ACETYL-L-GLUTAMIC ACID |
| CAS: | 1188-37-0 |
| MF: | C7H11NO5 |
| MW: | 189.17 |
| EINECS: | 214-708-4 |
| Product Categories: | Glutamic acid [Glu, E];Ac-Amino Acids;Amino Acid Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Amino Acid Derivatives;Glutamic Acid;Peptide Synthesis;amino acid;amino;1188-37-0 |
| Mol File: | 1188-37-0.mol |
| N-Acetyl-L-glutamic acid Chemical Properties |
| Melting point | 194-196 °C(lit.) |
| alpha | -16 º (c=1, water) |
| Boiling point | 324.41°C (rough estimate) |
| density | 1.4119 (rough estimate) |
| FEMA | 4752 | N-ACETYL GLUTAMATE |
| refractive index | -15 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | 36g/l (Lit.) |
| pka | 3.45±0.10(Predicted) |
| form | Solid |
| color | White |
| optical activity | [α]22/D 15.6°, c = 1 in H2O |
| Water Solubility | 2.7 g/100 mL (20 ºC) |
| BRN | 1727473 |
| CAS DataBase Reference | 1188-37-0(CAS DataBase Reference) |
| NIST Chemistry Reference | N-acetyl-l-glutamic acid(1188-37-0) |
| EPA Substance Registry System | L-Glutamic acid, N-acetyl- (1188-37-0) |
| Safety Information |
| Safety Statements | 24/25 |
| WGK Germany | 2 |
| RTECS | LZ9725000 |
| TSCA | Yes |
| HS Code | 29241900 |
| MSDS Information |
| Provider | Language |
|---|---|
| N-Acetyl-L-glutamic acid | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| N-Acetyl-L-glutamic acid Usage And Synthesis |
| Chemical Properties | white crystalline powder |
| Uses | N-Acetyl-L-glutamic Acid is the N-Acetyl analogue of the non-essential amino acid, L-glutamic acid (G596960). N-Acetyl-L-glutamic Acid activates carbamoyl phosphate synthetase in the urea cycle. |
| Uses | Substrate for acetylglutamate kinase. Inhibitor of N-acetyl-L-glutamate synthetase |
| Uses | N-Acetyl-L-glutamic acid is used as pharmaceutical intermediates. |
| Purification Methods | A likely impurity is glutamic acid. Crystallise it from boiling water. It inhibits N-acetyl-L-glutamate synthase. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1948 1961, Shigesada & Tatibana Eur J Biochem 84 285 1978, Coude Biochem Biophys Res Commun 102 1016 1981, Beilstein 4 IV 3047.] |
| N-Acetyl-L-glutamic acid Preparation Products And Raw materials |
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