(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
  • CAS No.:14347-78-5
Other grades of this product :
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Basic information
Uses
Product Name:(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol
Synonyms:L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL;L-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL;L-(-)-1,2-ISOPROPYLIDENEGLYCEROL;2,3-ISOPROPYLIDENE-SN-GLYCEROL;2,3-O-ISOPROPYLIDENE-L-GLYCEROL;(-)-2,3-O-ISOPROPYLIDENE-SN-GLYCEROL;R-GLYCEROL ACETONIDE;R-(-)-2,3-O-ISOPROPYLIDENEGLYCEROL
CAS:14347-78-5
MF:C6H12O3
MW:132.16
EINECS:604-360-5
Product Categories:Chiral Reagents;Heterocycles;Chiral Building Blocks;Dioxanes & Dioxolanes;Synthetic Organic Chemistry;Inhibitors;pharmacetical;Dioxolanes;Glycidyl Compounds, etc. (Chiral)
Mol File:14347-78-5.mol
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Chemical Properties
alpha -13.7 º (neat)
Boiling point 72-73 °C/8 mmHg (lit.)
density 1.062 g/mL at 25 °C (lit.)
refractive index n20/D 1.434
Fp 176 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.20±0.10(Predicted)
form Liquid
Specific Gravity1.062
color Clear colorless to light yellow
optical activity[α]20/D 13.7°, neat
Water Solubility miscible
Merck 14,5213
BRN 80117
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyRNVYQYLELCKWAN-RXMQYKEDSA-N
CAS DataBase Reference14347-78-5(CAS DataBase Reference)
NIST Chemistry ReferenceD-Acetone glycerol(14347-78-5)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
RTECS JI0400000
10
HS Code 29329990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol Usage And Synthesis
Uses(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a MEK inhibitor with antitumor activity.
Chemical Propertiescolourless liquid
UsesA MEK inhibitor
Uses(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-methanol may be used to prepare:
  • (R)-2,2-Dimethyl-4-benzoxymethyl-1,3-dioxolane.
  • ((S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate)-1,3-dioxolane.
  • (S)-Glyceraldehyde acetonide.
  • Tetraoxaspiroundecanes, diglycerides, glyceryl phosphates, and spiropyrans.

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