H2N-PEG8-tBu

H2N-PEG8-tBu
  • CAS No.:756526-06-4
Other grades of this product :
H2N-PEG8-tBu Basic information
Product Name:H2N-PEG8-tBu
Synonyms:Amino-PEG9-t-butyl ester;H2N-PEG8-CH2CH2COOtBu;H2N-PEG8-tBu;27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid 1,1-dimethylethyl ester;H2N-PEG8-CH2CH2COOtBu;Amino-PEG8-t-butyl ester;NH2-PEG8-CH2CH2COOtBu;tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
CAS:756526-06-4
MF:C23H47NO10
MW:497.62
EINECS:
Product Categories:peg
Mol File:756526-06-4.mol
H2N-PEG8-tBu Chemical Properties
Boiling point 544.3±45.0 °C(Predicted)
density 1.067±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Soluble in Water, DMSO, DCM, DMF
pka8.74±0.10(Predicted)
Safety Information
HS Code 2942000090
MSDS Information
H2N-PEG8-tBu Usage And Synthesis
DescriptionAmino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
UsesH2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.
H2N-PEG8-tBu Preparation Products And Raw materials
Raw materialsOCTAETHYLENE GLYCOL-->tert-Butyl acrylate

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