3-Ethoxy-4-methoxy benzonitrile
3-Ethoxy-4-methoxy benzonitrile
  • CAS No.:60758-86-3
Other grades of this product :
3-Ethoxy-4-methoxy benzonitrile Basic information
Product Name:3-Ethoxy-4-methoxy benzonitrile
Synonyms:Benzonitrile, 3-ethoxy-4-Methoxy-;3-ethoxy-4-Methoxybenzonitrile;3-Ethoxy-4-Methoxy benzontrile;3-Ethoxy-4-methoxybenzonitrile Apremilast;3-Ethoxy-4-methoxybenzonitril;Apremilast Impurity 2:3-Ethoxy-4-methoxybenzonitrile;3-Ethoxy-4-methoxy bezonitrile;3-Ethoxy-4-methoxybenzonitrile &gt
CAS:60758-86-3
MF:C10H11NO2
MW:177.2
EINECS:
Product Categories:apremilast intermediates;Apremilast
Mol File:60758-86-3.mol
3-Ethoxy-4-methoxy benzonitrile Chemical Properties
Melting point 70℃
Boiling point 281.9±25.0℃ (760 Torr)
density 1.09±0.1 g/cm3 (20 ºC 760 Torr)
Fp 109.2±16.4℃
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Light yellow
InChIKeyXTIINWPNAMHVDG-UHFFFAOYSA-N
Safety Information
RIDADR 3439
HazardClass 6.1
PackingGroup III
HS Code 2926907090
MSDS Information
3-Ethoxy-4-methoxy benzonitrile Usage And Synthesis
Uses3-Ethoxy-4-methoxy benzonitrile can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
SynthesisIn a 100 ml flask in the, adding 3-hydroxy-4-methoxy phenyl nitrile 10g (67.11mmol), bromoethane 25 ml (335.2mmol), potassium carbonate 10.25g, dimethyl formamide 50 ml, heating and stirring to 100 °C. TLC monitoring reaction, reaction 8h, stop heating. Natural cooling to room temperature, water 100 ml, the ethyl acetate extraction, the organic phase is dried with anhydrous sodium sulfate, ethyl acetate solvent turns on lathe does the white solid obtained 11.09g.

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