Other grades of this product :
| 2,3-Dihydrobenzofuran Basic information |
| 2,3-Dihydrobenzofuran Chemical Properties |
| Melting point | -21°C | | Boiling point | 188-189 °C (lit.) | | density | 1.065 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.549(lit.) | | Fp | 152 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | alcohol: soluble | | form | clear liquid | | color | Colorless to Yellow to Green | | Specific Gravity | 1.065 | | Merck | 14,2559 | | BRN | 111928 | | InChIKey | HBEDSQVIWPRPAY-UHFFFAOYSA-N | | CAS DataBase Reference | 496-16-2(CAS DataBase Reference) | | NIST Chemistry Reference | Benzofuran, 2,3-dihydro-(496-16-2) | | EPA Substance Registry System | Coumaran (496-16-2) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 23-24/25-26 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29329995 |
| 2,3-Dihydrobenzofuran Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | 2,3-dihydrobenzofuran is widely used in the synthesis of tricyclic compounds and is also an intermediate raw material for the synthesis of some important drugs. It is used in the synthesis of antitumor agents benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, etc. | | Definition | ChEBI: 2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran. It has a role as a metabolite. | | General Description | Biotransformation of 2,3-dihydrobenzofuran using intact cells of Pseudomonas putida UV4 has been investigated. 2,3-Dihydrobenzofuran is the intermediate formed during catalytic hydrodeoxygenation of benzofuran. |
| 2,3-Dihydrobenzofuran Preparation Products And Raw materials |
| Raw materials | ETHYLIDENECYCLOHEXANE-->2-Chlorostyrene-->2-CHLOROPHENETHYLALCOHOL-->Benzofuran-->2-Chlorotoluene | | Preparation Products | 1-Benzofuran-5-carbaldehyde-->2,3-Dihydrobenzo[b]furan-5-carbaldehyde-->2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID-->2,3-DIHYDROBENZOFURAN-5-BORONIC ACID-->5-(AMINOMETHYL)-2,3-DIHYDROBENZO[B]FURAN-->5-ACETYL-2,3-DIHYDROBENZO(B)FURAN-->1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one-->2,3-DIHYDRO-1-BENZOFURAN-5-YLMETHANOL-->2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-ylethylamine-->2,3-Dihydro-1-benzofuran-5-propanoic acid-->Darifenacin-->5-Bromo-2,3-dihydro-1-benzofuran |
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