tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate

CAS No.：1628047-84-6

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tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Basic information

Product Name:	tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate
Synonyms:	tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate;tert-butyl 4-bromo-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;ABT199 intermediate 2;4-Bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoic acid 1,1-dimethylethyl ester;2575SM2;Benzoic acid, 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, 1,1-dimethylethyl ester;2-Methyl-2-propanyl 4-bromo-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
CAS:	1628047-84-6
MF:	C18H17BrN2O3
MW:	389.24
EINECS:	942-459-8
Product Categories:
Mol File:	1628047-84-6.mol

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Chemical Properties

Melting point	188 - 190°C
density	1.445±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), DMSO (Slightly)
pka	13.26±0.40(Predicted)
form	Solid
color	White to Off-White

Safety Information

MSDS Information

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Usage And Synthesis

Uses	tert-?Butyl 4-?Bromo-?2-?(1H-?pyrrolo[2,?3-?b]?pyridin-?5-?yloxy)benzoate is used in the synthesis of apoptosis-inducing agents. Intermediate of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.

tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Preparation Products And Raw materials

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