Product

N-Benzyloxycarbonyl-D-proline

CAS No.：6404-31-5

Other grades of this product :

N-Benzyloxycarbonyl-D-proline Basic information

Product Name:	N-Benzyloxycarbonyl-D-proline
Synonyms:	Cbz-D-Pro;PROLINA-Z-D;1,2-PYRROLIDINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL)ESTER, (2R)-;1,2-PYRROLIDINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL) ESTER, (R)-;1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID;(R)-Z-pyrrolidine-2-carboxylic acid;Z-D-proline≥ 98% (HPLC);BENZYLOXYCARBONYL-D-PROLINE
CAS:	6404-31-5
MF:	C13H15NO4
MW:	249.26
EINECS:	229-021-5
Product Categories:	Amino Acids;Amino Acids (N-Protected);Proline [Pro, P];Biochemistry;Cbz-Amino Acids;Cbz-Amino acid series;Z-Amino Acids and Derivatives;Amino Acid Derivatives;Peptide Synthesis;Proline
Mol File:	6404-31-5.mol

N-Benzyloxycarbonyl-D-proline Chemical Properties

Melting point	76-78 °C(lit.)
alpha	40 º (c=2, EtOH)
Boiling point	432.3±45.0 °C(Predicted)
density	1.309±0.06 g/cm3(Predicted)
refractive index	40 ° (C=2, EtOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka	3.99±0.20(Predicted)
form	Crystalline Powder or Powder
color	White
optical activity	[α]25/D +40.2°, c = 2 in ethanol
BRN	485188
InChIKey	JXGVXCZADZNAMJ-LLVKDONJSA-N
CAS DataBase Reference	6404-31-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

N-Benzyloxycarbonyl-D-proline Usage And Synthesis

Chemical Properties	White crystalline powder or powder
Uses	N-(Benzyloxycarbonyl)-D-proline is an an N-Cbz-protected form of D-proline (P755990). It is used to prepare trichostatin A and trapoxin B analogs as histone deacetylase inhibitors. It is also used to prepare potent and selective nonpeptide inhibitors of caspases 3 and 7.

N-Benzyloxycarbonyl-D-proline Preparation Products And Raw materials

Preparation Products

(R)-5-BROMO-3-[(1-METHYL-2-PYRROLIDINYL)METHYL]-1H-INDOLE

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