POLY(2-HYDROXYETHYL METHACRYLATE)

POLY(2-HYDROXYETHYL METHACRYLATE)
  • CAS No.:25249-16-5
Other grades of this product :
POLY(2-HYDROXYETHYL METHACRYLATE) Basic information
Product Name:POLY(2-HYDROXYETHYL METHACRYLATE)
Synonyms:POLY(2-HEMA);POLY(2-HYDROXYETHYL METHACRYLATE);POLY-HEMA;polyhydroxyethylmethacrylate;Poly(2-hydroxyethyl methacrylate),Poly(2-HEMA), Poly-HEMA;POLY(2-HYDROXYETHYL METHACRYLATE), MV CA;POLY(2-HYDROXYETHYL METHACRYLATE) CELL*C ULTURE TEST;POLY(2-HYDROXYETHYL METHACRYLATE), AVERA GE MV CA. 300,000
CAS:25249-16-5
MF:C6H10O3
MW:130.14
EINECS:
Product Categories:Acrylics;and Related Polymers;Contact Printing;Ethacrylate;Hydrophilic Polymers;Materials Science;Methacrylate;Micro/NanoElectronics;Microcontact Printing;PMMA-Based Resins;Polymer Science;Polymers;Self Assembly &Stamps for Nanoprint Lithography &amp
Mol File:25249-16-5.mol
POLY(2-HYDROXYETHYL METHACRYLATE) Chemical Properties
density 1.15 g/mL at 25 °C(lit.)
solubility ethanol: 120 mg/mL
form powder
EPA Substance Registry System2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer (25249-16-5)
Safety Information
Safety Statements 24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
POLY(2-HYDROXYETHYL METHACRYLATE) Usage And Synthesis
UsesPoly(2-hydroxyethyl methacrylate) has been used:
  • as a nonadhesive substrate in the preparation of single cell suspensions
  • to implant into mice cornea for corneal micropocket assay
  • to coat the well plates for sphere assay using adipose-derived mesenchymal stem cells
UsespHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.
DefinitionChEBI: An acrylate macromolecule, composed of repeating 2-hydroxyethyl 2-methylpropanoate units.
General DescriptionSolid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.
Biochem/physiol ActionsPoly(2-hydroxyethyl methacrylate) is an acrylic compound and has dental usage. It is mainly used to inhibit cell adhesion to growth surfaces in culture vessels.
POLY(2-HYDROXYETHYL METHACRYLATE) Preparation Products And Raw materials

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