LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
  • CAS No.:71800-36-7
Other grades of this product :
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Basic information
Product Name:LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
Synonyms:(DES-ARG10)-KALLIDIN;[DES-ARG9,LYS0]-BRADYKININ;H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-OH;LYS-(DES-ARG9)-BRADYKININ;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE;LYSYL-DES-ARG9-BRADYKININ;[LYS0, DES-ARG9]-BRADYKININ;des-arg(10)-kallidi
CAS:71800-36-7
MF:C50H73N13O11
MW:1032.2
EINECS:
Product Categories:Bradykinin receptor
Mol File:71800-36-7.mol
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Chemical Properties
storage temp. −20°C
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Usage And Synthesis
Uses[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage.
Biochem/physiol Actions[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells.
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Preparation Products And Raw materials

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