Product

N-Carbobenzyloxy-L-valine

CAS No.：1149-26-4

Other grades of this product :

N-Carbobenzyloxy-L-valine Basic information

Product Name:	N-Carbobenzyloxy-L-valine
Synonyms:	Z-VAL;Z-VALINE;Z-VAL-OH;N-Carbobenzyloxy-L-valine Cbz-L-Valine;CBZ-L-Valine (Z-Val-OH);Z-L-VALINE;Z-L-VAL-OH;N-Cbz-L-valine Z-Val-OH
CAS:	1149-26-4
MF:	C13H17NO4
MW:	251.28
EINECS:	214-562-1
Product Categories:	Valine [Val, V];Z-Amino Acids and Derivatives;Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Miscellaneous Biochemicals;chiral;PROTECTED AMINO ACID & PEPTIDES;Chiral Compounds;Cbz-Amino acid series
Mol File:	1149-26-4.mol

N-Carbobenzyloxy-L-valine Chemical Properties

Melting point	62-64 °C(lit.)
alpha	-4 º (c=2,acetic acid)
Boiling point	394.43°C (rough estimate)
density	0,926g/cm
refractive index	-4.3 ° (C=2, AcOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Acetic Acid, DMSO (Slightly), Ethanol (Slightly)
form	Crystalline Powder
pka	4.00±0.10(Predicted)
color	White to off-white
optical activity	[α]20/D 4.2±0.5°, c = 2 in chloroform
BRN	2056617
InChIKey	CANZBRDGRHNSGZ-NSHDSACASA-N
CAS DataBase Reference	1149-26-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	38-43-36/37/38-20/21/22
Safety Statements	36/37-36-26
WGK Germany	3
Hazard Note	Irritant
HS Code	29242990

MSDS Information

Provider	Language
2-{[(Benzyloxy)carbonyl]amino}-3-methylbutanoic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

N-Carbobenzyloxy-L-valine Usage And Synthesis

Chemical Properties	white to light yellow crystal powde
Uses	Imatinib intermediate
Uses	Valaciclovir intermediate
Uses	N-Cbz-L-valine is an N-Cbz-protected form of L-Valine (V094205). L-Valine is an essential amino acid that is used as an ingredient in cosmetic formulations, pharmaceuticals, and animal feed products. L-valine is also important for growth and ammonia detoxification in humans.
Synthesis Reference(s)	Synthesis, p. 738, 1985 DOI: 10.1055/s-1985-31329

N-Carbobenzyloxy-L-valine Preparation Products And Raw materials

Preparation Products

H-VAL-VAL-OH-->tert-Butyl L-valinate-->tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate-->Z-VAL-OSU

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