trans-DL-1,2-Cyclopentanedicarboxylic acid

CAS No.：1461-97-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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trans-DL-1,2-Cyclopentanedicarboxylic acid Basic information

Product Name:	trans-DL-1,2-Cyclopentanedicarboxylic acid
Synonyms:	1,2-CYCLOPENTANEDICARBOXYLIC ACID:98+%;trans-Cyclopentane-1,2-dicarboxylic acid;1,2-Cyclopentane DiforMic Acid;trans-DL-1,2-Cyclopentanedicarboxylic acid;Transpentane-1,2-dicarboxylic acid;TRANS-DL-1,2-CYCLOPENTANEDICARBOXYLIC ACID;TRANS-DL-CYCLOPENTANE-1,2-DICARBOXYLIC ACID;trans-DL-1,2-Cyclopentanedicarboxylic acid 98%
CAS:	1461-97-8
MF:	C7H10O4
MW:	158.15
EINECS:	215-962-9
Product Categories:	Carboxylic Acid Monomers;Monomers;Polymer Science
Mol File:	1461-97-8.mol

trans-DL-1,2-Cyclopentanedicarboxylic acid Chemical Properties

Melting point	163-165 °C(lit.)
Boiling point	46-49 °C(Press: 110 Torr)
density	1.396±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO; Methanol
pka	pK1:3.96;pK2:5.85 (25°C)
form	Solid
color	Off-white
EPA Substance Registry System	1,2-Cyclopentanedicarboxylic acid, (1R,2R)-rel- (1461-97-8)

Safety Information

WGK Germany	3
HS Code	2917200090

MSDS Information

Provider	Language
SigmaAldrich	English

trans-DL-1,2-Cyclopentanedicarboxylic acid Usage And Synthesis

Chemical Properties	off-white powder
Uses	trans-1,2-Cyclopentanedicarboxylic Acid is used as a reagent in the synthesis of isoxazoline and oxazoline analogs of CDA54 as voltage gated sodium channel blockers. trans-1,2-Cyclopentanedicarboxylic Acid is also a reagent in the preparation of cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.

trans-DL-1,2-Cyclopentanedicarboxylic acid Preparation Products And Raw materials

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