N-Acetyl-L-tyrosine

N-Acetyl-L-tyrosine
  • CAS No.:537-55-3
Other grades of this product :
N-Acetyl-L-tyrosine Chemical Properties
Melting point 149-152 °C(lit.)
alpha 47.5 º (c=2, water)
Boiling point 364.51°C (rough estimate)
density 1.2446 (rough estimate)
refractive index 1.4960 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility H2O: soluble25mg/mL
form Crystalline
pka3.15±0.10(Predicted)
color White to Off-White
Water Solubility Soluble in water (25 mg/ml), and ethanol.
BRN 2697172
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference537-55-3(CAS DataBase Reference)
NIST Chemistry ReferenceN-acetyl-Tyr(537-55-3)
EPA Substance Registry SystemN-Acetyl-L-tyrosine (537-55-3)
Safety Information
Hazard Codes Xi
Risk Statements 41-36/37/38
Safety Statements 26-39-36
WGK Germany 3
10
TSCA Yes
HS Code 29242995
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
N-Acetyl-L-tyrosine Usage And Synthesis
Chemical PropertiesN-Acetyl-L-Tyrosine is a white crystalline powder that is an acetyl derivative of the amino acid, L-tyrosine. It is freely soluble in water compared to L-tyrosine and is commonly used as a parenteral nutrition supplement. N-Acetyl-L-tyrosine , a stable and more soluble form of tyrosine , has been incorporated in some currently available commercial parenteral amino acid formulations such as TrophAmine and Aminosyn-II.
UsesN-Acetyl-L-tyrosine is involved in catecholamine production. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.
DefinitionChEBI: N-acetyl-L-tyrosine is an N-acetyltyrosine in which the chiral centre has L configuration. It has a role as an EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor, a biomarker and a human urinary metabolite. It is a N-acyl-L-tyrosine and a N-acetyltyrosine. It is a conjugate acid of a N-acetyl-L-tyrosinate.
ApplicationN-Acetyl-L-tyrosine is a tyrosine derivative with a chemical structure similar to that of an amino acid. It is used as a model system in biochemistry and molecular biology to study the transfer reactions of tyrosine, which are important for energy metabolism, protein synthesis, and metal chelation. N-acetyl-L-tyrosine may be used as an indicator to distinguish neurosyphilis patients from syphilis/non-neurosyphilis patients. N-acetyl-L-tyrosine is a precursor of the essential neurotransmitter dopamine.
benefitsN-Acetyl-L-Tyrosine (NALT) plays a necessary part in the synthesis of dopamine and other hormones in your body. It can boost levels of the neurotransmitters dopamine, norepinephrine and epinephrine. It helps to support higher levels of focus and cognitive function. It can increase working memory and feelings of well-being.
Side effectsL-tyrosine gets the generally regarded as safe (GRAS) stamp of approval from the FDA. Some side effects of N-Acetyl-L-tyrosine (NALT) include nausea, headache, fatigue, and heartburn. It can be safely taken for extended periods of time.

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