L-Norleucine

L-Norleucine
  • CAS No.:327-57-1
Other grades of this product :
L-Norleucine Basic information
Product Name:L-Norleucine
Synonyms:alpha-aminocaproic acid;L(+)-Norleucine, 99+% 1GR;Norleucine Solution;(S)-Norleucine;Norleucine, L- (8CI);Glycoleucine;Hexanoic acid, 2-amino-, (S)-;n-C4H9CH(NH2)COOH
CAS:327-57-1
MF:C6H13NO2
MW:131.17
EINECS:206-321-4
Product Categories:Amino Acids;Amino Acids;Leucine [Leu, L];Unusual Amino Acids;Amino Acids & Derivatives;Isotope Labelled Compounds
Mol File:327-57-1.mol
L-Norleucine Chemical Properties
Melting point >300 °C (lit.)
alpha 22 º (c=2, 6N HCl)
density 1.1720 (estimate)
refractive index 23 ° (C=5, 5mol/L HCl)
Fp 275 °C
storage temp. Sealed in dry,Room Temperature
solubility 1.6 g/100 mL (23°C)
pka2.335(at 25℃)
Boiling point 234.0±23.0 °C(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility 1.6 g/100 mL (23 ºC)
Sublimation 275 ºC
Merck 14,6706
BRN 1721750
CAS DataBase Reference327-57-1(CAS DataBase Reference)
NIST Chemistry ReferenceL-Norleucine(327-57-1)
EPA Substance Registry SystemL-Norleucine (327-57-1)
Safety Information
Hazard Codes Xi
Risk Statements 43
Safety Statements 36/37-24/25-22
WGK Germany 3
RTECS RC6308000
TSCA Yes
HS Code 29224995
MSDS Information
ProviderLanguage
alpha-Aminocaproic acid English
ACROS English
SigmaAldrich English
ALFA English
L-Norleucine Usage And Synthesis
Chemical Propertieswhite to off-white crystalline powder
UsesAs a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.
UsesA non-essential amino acid. Used as internal standard in amino acid analysis.
DefinitionChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.
Biochem/physiol ActionsL-Norleucine is a synthetic amino acid commonly used as an internal standard.
Purification MethodsCrystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]
L-Norleucine Preparation Products And Raw materials
Preparation ProductsFMOC-NLE-OH-->DL-Norleucine-->H-NLE-OME HCL-->BOC-L-NORLEUCINE

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