Other grades of this product :
| Raubasine Basic information |
| Raubasine Chemical Properties |
| Melting point | 258°C (rough estimate) | | Boiling point | 486.04°C (rough estimate) | | alpha | D20 -60° (c = 0.5 in chloroform); D20 -45° (c = 0.5 in pyridine); D20 -39° (c = 0.25 in methanol) | | density | 1.1823 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | pK1:10.55(+1) (25°C) | | color | Pale Yellow | | optical activity | [α]/D -65±3°, c = 1 in chloroform | | BRN | 97268 | | NIST Chemistry Reference | Ajmalicine(483-04-5) |
| Hazard Codes | Xn | | Risk Statements | 25-22 | | Safety Statements | 22-45 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | AX7875000 | | HazardClass | 6.1(b) | | PackingGroup | III |
| Raubasine Usage And Synthesis |
| Description | Vinca rosea L. yields this alkaloid which crystallizes as colourless needles from MeOH.
The base is laevorotatory having a specific rotation of [α]D_620 (MeOH) and forms
a crystalline hydrochloride, m.p. 281-3°e. The structure given above has been
elucidated from chemical and spectroscopic data. | | Uses | Antihypertensive, anti-ischemic. | | Uses | Antihypertensive, anti-ischemic (cerebral and peripheral) | | Purification Methods | It crystallises from MeOH, EtOH or EtOAc. [Beilstein 27 III/IV 7927.] | | References | Janot, Le Men, Cornpt. Rend., 243, 1786 (1956)
Shamma, Moss, J. Arner. Chern. Soc., 83, 5038 (1961)
Abdurakhsimova, Yuldashev, Yunusov, Khirn. Prir. Soedin., 1,224 (1965) |
| Raubasine Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye