N-Benzoylaminopurine

N-Benzoylaminopurine
  • CAS No.:4005-49-6
Other grades of this product :
N-Benzoylaminopurine Basic information
Product Name:N-Benzoylaminopurine
Synonyms:6-BENZOYLAMINOPURINE;6-BENZAMIDOPURINE;N6-BENZOYLAMINOPURINE;N6-BENZOYLADENINE;N-BZ-ADE;N-BENZOYLADENINE;N-BENZOYLAMINOPURINE;N-Benzolaminopurine
CAS:4005-49-6
MF:C12H9N5O
MW:239.23
EINECS:629-048-6
Product Categories:Purine;Biochemicals and Reagents;Biochemistry;Nucleobases and their analogs;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides;Nucleosides, Nucleotides & Related Reagents
Mol File:4005-49-6.mol
N-Benzoylaminopurine Chemical Properties
Melting point 242-244°C
density 1.494 g/cm3
storage temp. 2-8°C
Water Solubility Insoluble in water
pka11.98±0.20(Predicted)
form powder to crystal
color White to Almost white
BRN 20585
CAS DataBase Reference4005-49-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-43
Safety Statements 36/37
WGK Germany 3
Hazard Note Irritant
HS Code 29335990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
N-Benzoylaminopurine Usage And Synthesis
Chemical PropertiesWhite solid
UsesN-Benzoylaminopurine is used in the organic synthesis of adenine derivative molecules such as bicyclic adenine nucleoside via a condensation reaction between L-threo-pentofuranose derivative 1 and 6-N-benzoyladenine and to produce oxy-peptide nucleic acids.
UsesN6-Benzoyladenine is used in the organic synthesis of adenine derivative molecules such as bicyclic adenine nucleoside via a condensation reaction between L-threo-pentofuranose derivative 1 and 6-N-benzoyladenine and to produce oxy-peptide nucleic acids.
Biochem/physiol ActionsN6-Benzoyladenine comprises of adenine moiety and is a potent inhibitor of bromodomain-containing protein 4 (BRD4). N6-Benzoyladenine modulates tumor necrosis factor α (TNF-α) levels. It elicits cytotoxicity in liver and ileum cancer cells and may serve as a potential candidate agent for cancer chemotherapy.

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