L-(+)-Glutamic acid hydrochloride

L-(+)-Glutamic acid hydrochloride
  • CAS No.:138-15-8
Other grades of this product :
L-(+)-Glutamic acid hydrochloride Basic information
Product Name:L-(+)-Glutamic acid hydrochloride
Synonyms:2-aminopentanedioicacidhydrochloride;acidalin;acidogen;acidoride;acidothyn;acidulen;acidulin;aciglumin
CAS:138-15-8
MF:C5H10ClNO4
MW:183.59
EINECS:205-315-9
Product Categories:alpha-Amino Acids;Amino Acids;Biochemistry;Amino acid
Mol File:138-15-8.mol
L-(+)-Glutamic acid hydrochloride Chemical Properties
Melting point 214 °C (dec.)(lit.)
alpha 25.5 º (c=10, 2N HCl)
density 1.525
refractive index 24 ° (C=6, H2O)
storage temp. Store below +30°C.
solubility H2O: 1 M at 20 °C, clear, colorless
form Crystals For Fine Crystalline Powder
color White
Water Solubility 490 g/L (20 ºC)
Sensitive Hygroscopic
Merck 14,4469
BRN 3565569
Stability:Hygroscopic
CAS DataBase Reference138-15-8(CAS DataBase Reference)
EPA Substance Registry SystemL-Glutamic acid, hydrochloride (138-15-8)
Safety Information
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-39
RIDADR UN 1789 8/PG 3
WGK Germany 3
3-10
TSCA Yes
HS Code 29224200
MSDS Information
ProviderLanguage
L-(+)-Glutamic acid hydrochloride English
SigmaAldrich English
ACROS English
ALFA English
L-(+)-Glutamic acid hydrochloride Usage And Synthesis
Chemical Propertieswhite crystals or fine crystalline powder
UsesGlutamic Acid Hydrochloride is a flavoring, salt substitute that is soluble in water and very slightly soluble in alcohol and ether. It is obtained by chemical synthesis.
UsesL-Glutamic acid hydrochloride is used as a digestive aid. It is used in cell culture as a component of MEM non-essential amino acids solution. It has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production.
General DescriptionL-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.
Biochem/physiol ActionsL-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington′s disease and Parkinson′s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.

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