Polyquaternium-10

Polyquaternium-10
  • CAS No.:81859-24-7

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
Polyquaternium-10 Basic information
Product Name:Polyquaternium-10
Synonyms:HYDROXYETHYL-CELLULOSE-ETHOXYLAT, QUATERNISIERT;cellulose 2-hydroxyethyl 2-[2-hydroxy-3-(trimethylammonio)propoxy]ethyl 2-hydroxy-3-(trimethylammonio)propyl ether chloride;cellulose ether with a-[2-hydroxy-3-(trimethylammonio)propyl]-w-hydroxypoly(oxy-1,2-ethanediyl) chloride;Cellulose, 2-hydroxyethyl 2-2-hydroxy-3-(trimethylammonio)propoxyethyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride;QUATERNIUM-19;Polyquaternium-10 (1000 MPA.S at 2%);(55353-19-0;Polyquaternium-10
CAS:81859-24-7
MF:C8H6O6
MW:198.12964
EINECS:210-239-4
Product Categories:Polymers
Mol File:81859-24-7.mol
Polyquaternium-10 Chemical Properties
Melting point 290 °C(lit.)
EPA Substance Registry SystemCellulose, 2-hydroxyethyl 2-[2-hydroxy-3-(trimethylammonio)propoxy]ethyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride (81859-24-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
ToxicityLD50 oral in rat: > 2gm/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
Polyquaternium-10 Usage And Synthesis
DescriptionPolyquaternium 10 is a range of polymeric quaternary ammonium salts of hydroxyethyl cellulose (HEC) reacted with trimethyl ammonium substituted epoxide. Polyquaternium 10 solutions are non-Newtonian and are commercially available 1) in several viscosity grades depending on their molecular weights (they contribute to viscosity of formulations), and 2) with“high” to “moderate”cationic substitution. In vivo tests showed that these cationic cellulosic polymers protect the skin from aggression by anionic surfactants.
UsesPolyquaternium-10 (PQ-10) and Polyquaternium-7 (PQ-7) are two of the most frequently used polymers in commercial shampoos. Both of these polymers form negatively charged complexes with excess anionic surfactant, resulting in reduced deposition because of repulsion by the negatively charged hair surface. The magnitude of this effect depends on the particular anionic used, and on the anionic surfactant/polymer ratio. In all cases, however, conditioning from shampoos is significantly less than from stand-alone conditioners.
UsesPolyquaternium 10 is used for hair conditioning and protection.
Usespolyquaternium-10 is a cellulose polymer and conditioning agent used in skin-conditioning formulations. There are numerous cationic polymers that provide conditioning benefits, especially improved wet combing and reduced static charge. Important examples of these polymers are Polyquaternium-10, a quaternized hydroxyethylcellulose polymer; Polyquaternium-7, a Hair Conditioners 339 copolymer of diallyldimethylammonium chloride and acrylamide; Polyquaternium-11, a copolymer of vinylpyrrolidone and dimethylaminoethyl methacrylate quaternized with dimethyl sulfate; Polyquaternium-16, a copolymer of vinylpyrrolidone and quaternized vinylimidazole; and Polyquaternium-6, a homopolymer of diallyldimethylammonium chloride.
Polyquaternium-10 Preparation Products And Raw materials

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