Other grades of this product :
| Triisopropylsilane Basic information |
| Triisopropylsilane Chemical Properties |
| Boiling point | 84-86 °C/35 mmHg (lit.) | | density | 0.773 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.434(lit.) | | Fp | 99 °F | | storage temp. | Store below +30°C. | | form | liquid | | Specific Gravity | 0.773 | | color | colorless | | Water Solubility | Immiscible with water. | | Sensitive | Moisture Sensitive | | Hydrolytic Sensitivity | 3: reacts with aqueous base | | BRN | 1733718 | | InChIKey | YDJXDYKQMRNUSA-UHFFFAOYSA-N | | CAS DataBase Reference | 6485-79-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 26-36-37/39-16 | | RIDADR | UN 1993 3/PG 3 | | WGK Germany | 3 | | F | 10-21 | | TSCA | No | | HS Code | 2931 90 00 | | HazardClass | 3 | | PackingGroup | III |
| Triisopropylsilane Usage And Synthesis |
| Chemical Properties | Clear colorless liquid | | Uses | The bulky isopropyl groups (vs. ethyl) allow for more selective reductions, e.g., beta-selective reduction of anomeric C-phenyl ketals, but do not diminish their activity (e.g. in the copper triflate catalyzed reductive etherification of trimethylsilyl ethers). | | Uses | Selective silylation of primary hydroxy groups in the presence of secondary alcohol. | | Uses | Triisopropylsilane is used as a protecting group in peptide synthesis and is also used as a reducing agent for the selective reduction of anomeric C-phenyl ketals. It is used in the selective silylation of primary hydroxyl groups without affecting the secondary hydroxyl group. It is used in the preparation of anti-1,2-diols catalyzed by a Ni(O) N-heterocyclic carbine complex with high diastereoselectivity. | | Application | Very sterically-hindered silane. Used as a cation
scavenger in the deprotection of peptides. |
| Triisopropylsilane Preparation Products And Raw materials |
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