3-Chloro-L-tyrosine

CAS No.：7423-93-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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3-Chloro-L-tyrosine Basic information

Product Name:	3-Chloro-L-tyrosine
Synonyms:	3-Chloro-4-hydroxy-L-phenylalanine~H-Tyr(3-Cl)-OH;3-CHLORO-L-TYROSINE;3-CL-TYR-OH;3-CHLOROTYROSINE;H-TYR(3-CL)-OH;H-3-CHLORO-L-TYR-OH;CHLORO-L-TYROSINE, 3-;3-Cl-L-Tyr-OH
CAS:	7423-93-0
MF:	C9H10ClNO3
MW:	215.63
EINECS:	231-050-3
Product Categories:	Tyrosine [Tyr, Y];Unusual Amino Acids;PROTECTED AMINO ACID & PEPTIDES;Peptide Synthesis;Tyrosine Derivatives;Unnatural Amino Acid Derivatives
Mol File:	7423-93-0.mol

3-Chloro-L-tyrosine Chemical Properties

Melting point	249 °C (lit.)
alpha	-2 º (c=1 in 1 M HCl)
Boiling point	388.6±42.0 °C(Predicted)
density	1.458±0.06 g/cm3(Predicted)
storage temp.	Store at RT.
solubility	Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly), Water (Slig
pka	2.21±0.20(Predicted)
form	Solid
color	White to Off-White
optical activity	[α]24/D 2°, c = 1 in 1 M HCl
BRN	2941263
Stability:	Hygroscopic
CAS DataBase Reference	7423-93-0(CAS DataBase Reference)

Safety Information

Safety Statements	22-24/25
WGK Germany	3
HS Code	2922500090

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

3-Chloro-L-tyrosine Usage And Synthesis

Chemical Properties	White to off-white powder
Uses	3-Chloro-L-tyrosine was used in the enzymatic synthesis of halogen derivatives of aromatic amino acids labeled with hydrogen isotope. 3-Chloro-L-tyrosine exhibited stronger antioxidant properties in Hb-induced oxidative stress as was evident by higher efficiency of reduction of ferryl species.
Definition	ChEBI: A chloroamino acid comprising a tyrosine core with a chloro- substituent ortho to the phenolic hydroxy group.

3-Chloro-L-tyrosine Preparation Products And Raw materials

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