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| H2N-PEG4-Propyne Basic information |
| Product Name: | H2N-PEG4-Propyne | | Synonyms: | Acetylene-PEG4-amine;Amino-PEG4-alkyne;Triethylene glycol 2-aminoethyl propargyl ether;Propargyl-PEG4-amine;HC≡C-CH2-PEG4-NH2;Propyne-PEG4-amine;1-Amino-3,6,9,12-tetraoxapentadec-14-yne;Alkyne-PEG4-Amine | | CAS: | 1013921-36-2 | | MF: | C11H21NO4 | | MW: | 231.29 | | EINECS: | | Product Categories: | Heterobifunctional PEG;peg | | Mol File: | 1013921-36-2.mol |
| H2N-PEG4-Propyne Chemical Properties |
| Boiling point | 315.9±32.0 °C(Predicted) | | density | 1.037±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO, DMF, DCM, THF, or chloroform. | | pka | 8.74±0.10(Predicted) | | form | Solid | | color | Pale Yellow |
| H2N-PEG4-Propyne Usage And Synthesis |
| Description | Propargyl-PEG4-amine has a propargyl group and an amine group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls, etc. The propargyl group can form triazole linkage with azide-bearing biomolecules. | | Uses | 1-Amino-3,6,9,12-tetraoxapentadec-14-yne is used as a acetylene containing reagent with PEG spacer and carboxyl reactivity. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character. |
| H2N-PEG4-Propyne Preparation Products And Raw materials |
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