5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione

5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
  • CAS No.:830346-48-0
Other grades of this product :
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Basic information
Product Name:5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
Synonyms:5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione;Elagolix Impurity 19;5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one;1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-bromo-6-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-;5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
CAS:830346-48-0
MF:C13H9BrF4N2O2
MW:381.12
EINECS:
Product Categories:
Mol File:830346-48-0.mol
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Chemical Properties
Melting point >230°C (dec.)
density 1.684±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka7.83±0.40(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Usage And Synthesis
Uses5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Preparation Products And Raw materials
Preparation Products5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione

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