Product

(R)-(+)-2-Chloropropionic acid

CAS No.：7474-05-7

Other grades of this product :

(R)-(+)-2-Chloropropionic acid Basic information

Product Name:	(R)-(+)-2-Chloropropionic acid
Synonyms:	(R)-(+)-2-Chloropropionic Acid;(R)-(+)-2-Chloropropionic acid,98%;(R)-(+)-2-CHLOROPROPIONIC ACID FOR SYNTH;(R)-(+)-2-Chloropropionic acid 99%;(2R)-(+)-2-Chloropropanoic acid 98%;(2R)-(+)-2-Chloropropanoic acid;R(+)-2-Chloropropionic acid≥ 98% (Assay);(R)-2-Chloropropionic Acid,99%e.e.
CAS:	7474-05-7
MF:	C3H5ClO2
MW:	108.52
EINECS:	626-432-5
Product Categories:	Synthetic Organic Chemistry;Carboxylic Acids;Miscellaneous Reagents;Carboxylic Acids (Chiral);Chiral Building Blocks;Organic Building Blocks;chiral;CHIRAL COMPOUNDS;Chiral Building Blocks
Mol File:	7474-05-7.mol

(R)-(+)-2-Chloropropionic acid Chemical Properties

Melting point	-12°C
Boiling point	185-188 °C (lit.)
alpha	14 º (neat)
density	1.258 g/mL at 20 °C (lit.)
refractive index	n20/D 1.4345(lit.)
Fp	140 °F
storage temp.	−20°C
pka	2.96±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
optical activity	[α]20/D +14°, neat
BRN	1720258
CAS DataBase Reference	7474-05-7(CAS DataBase Reference)

Safety Information

Hazard Codes	C
Risk Statements	22-35
Safety Statements	23-26-28-36-45
RIDADR	UN 2511 8/PG 3
WGK Germany	3
HazardClass	8
PackingGroup	III
HS Code	29159000

MSDS Information

Provider	Language
SigmaAldrich	English

(R)-(+)-2-Chloropropionic acid Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:???????

Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.???????
(R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.???????
2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.

(R)-(+)-2-Chloropropionic acid Preparation Products And Raw materials

Raw materials	2-Pentene, 4-chloro--->[R,(+)]-2-Chloropropionic acid ethyl ester-->D-Alanine
Preparation Products	(S)-(-)-2-Chloropropionic acid-->(R)-(-)-2-Chloropropan-1-ol-->(S)-1-OCTYN-3-OL-->Methanol

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