L-LEUCIC ACID

L-LEUCIC ACID
  • CAS No.:13748-90-8
Other grades of this product :
L-LEUCIC ACID Basic information
Product Name:L-LEUCIC ACID
Synonyms:(s)-pentanoicaci;(S)-(-)-2-HYDROXYISOCAPROIC ACID;(S)-2-HYDROXY-4-METHYLVALERIC ACID;2-HYDROXY-3-METHYLVALERIC ACID;2-HYDROXY-3-METHYLPENTANOIC ACID;L-2-hydroxy-4-methylvaleric acid;LEUCIC ACID;L-LEUCIC ACID
CAS:13748-90-8
MF:C6H12O3
MW:132.16
EINECS:237-329-6
Product Categories:API intermediates;Carboxylic Acids (Chiral);chiral;Chiral Building Blocks;Synthetic Organic Chemistry
Mol File:13748-90-8.mol
L-LEUCIC ACID Chemical Properties
Melting point 78-80 °C(lit.)
Boiling point 277.83°C (rough estimate)
density 1.0160 (rough estimate)
refractive index -26 ° (C=2, 1 %NaOH)
storage temp. Sealed in dry,Room Temperature
solubility Aqueous Base (Slightly), DMSO (Sparingly), Water (Slightly)
form Solid
pka3.86±0.21(Predicted)
color White to Off-White
optical activity[α]22/D 26.3°, c = 1 in 1 M NaOH
Water Solubility almost transparency
CAS DataBase Reference13748-90-8(CAS DataBase Reference)
EPA Substance Registry SystemPentanoic acid, 2-hydroxy-4-methyl-, (2S)- (13748-90-8)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29181990
MSDS Information
ProviderLanguage
SigmaAldrich English
L-LEUCIC ACID Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesL-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors.
DefinitionChEBI: The (S)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Derived from the metabolism of the branched-chain amino acids, it belongs to the 2-hydroxycarboxylic acid group of amino acid metabolites.

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