Other grades of this product :
| Chrysin Chemical Properties |
| Melting point | 284-286 °C(lit.) | | Boiling point | 357.45°C (rough estimate) | | density | 1.2693 (rough estimate) | | refractive index | 1.4872 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.50±0.40(Predicted) | | form | Crystalline Powder | | color | Yellow | | Merck | 14,2256 | | BRN | 233276 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | RTIXKCRFFJGDFG-UHFFFAOYSA-N | | CAS DataBase Reference | 480-40-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-36-26 | | WGK Germany | 3 | | RTECS | LK8329050 | | F | 10 | | HazardClass | IRRITANT | | HS Code | 29329990 |
| Chrysin Usage And Synthesis |
| Prepration | The main sources of chrysin are
honey and propolis, of which the content of chrysin in honey is 5.3
mg/kg and that in propolis is 28 g/L. In addition, chrysin is also found
in various vegetables, fruits, herbs, and even mushrooms [10]. Another
source of populin is an endophytic fungus Chaetomium globosum, which is
related to Chaetomorpha media from India. In addition, chrysin exists in
the form of glycosides in walnut, walnut skin, walnut flower and
pericarp passion fruit, and in the form of 6-c-arabinoside-8-c-glucoside
or glucuronic acid ester in Pinellia ternata. | | Description | Chrysin is a natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells. Chrysin inhibits insulin-induced HIF-1α expression (~50% at 10 μM) in human prostate cancer DU145 cells and blocks DU145 xenograft-induced angiogenesis in vivo. In a mouse model of ischemia/reperfusion injury, chrysin decreased pro-inflammatory gene expression and oxidative stress, resulting in a reduction of infarct volume and neurological defects. | | Physical properties | beige powder | | Uses | Chrysin is a flavanoid with anti-inflammatory effect and potential protective effects against cancer and cardiovascular disease. Studies show that Chrysin is central benzodiazepine receptor ligand wit
h possible anxiolytic effects. Chrysin was initially believed to have aromatase inhibitor but recent in vivo studies have disproved that. | | Uses | Chrysin is a flavanoid with anti-inflammatory effect and potential protective effects against cancer and cardiovascular disease. Studies show that Chrysin is central benzodiazepine receptor ligand with possible anxiolytic effects. Chrysin was initially believed to have aromatase inhibitor but recent in vivo studies have disproved that. Dyes and metabolites. | | Definition | ChEBI: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. |
| Chrysin Preparation Products And Raw materials |
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