4-Bromo-2-hydroxybenzaldehyde

4-Bromo-2-hydroxybenzaldehyde
  • CAS No.:22532-62-3
Other grades of this product :
4-Bromo-2-hydroxybenzaldehyde Basic information
Product Name:4-Bromo-2-hydroxybenzaldehyde
Synonyms:4-BROMO-2-HYDROXY-BENZALDEHYDE;4-Bromosalicylaldehyde;2-Hydroxy-4-Bromobenzaldehyde;4-Bromo-2-hydroxybenaldehyde;D1404;4-Bromosalicylaldehyde, 5-Bromo-2-formylphenol;4-BroMo-2-hydroxybenzaldheyde;Benzaldehyde,4-broMo-2-hydroxy-
CAS:22532-62-3
MF:C7H5BrO2
MW:201.02
EINECS:636-586-5
Product Categories:Aromatic Aldehydes & Derivatives (substituted);Aldehydes;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
Mol File:22532-62-3.mol
4-Bromo-2-hydroxybenzaldehyde Chemical Properties
Melting point 50-54 °C
Boiling point 48-52 °C(Press: 0.04 Torr)
density 1.737±0.06 g/cm3(Predicted)
Fp 110 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol.
form powder to crystal
pka7.21±0.10(Predicted)
color White to Light yellow to Light orange
CAS DataBase Reference22532-62-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,N,Xn
Risk Statements 22-50
Safety Statements 60
RIDADR UN 3077 9/PG 3
WGK Germany 3
Hazard Note Irritant
HazardClass 9
HS Code 2913000090
MSDS Information
4-Bromo-2-hydroxybenzaldehyde Usage And Synthesis
Chemical PropertiesOff-white powder
Uses4-Bromosalicylaldehyde is a substituted salicylaldehyde used in the synthesis of BIIB042, a γ-secretase modulator.
UsesIt is an important raw material and intermediate used in organic synthesis, Pharmaceuticals, agrochemicals and dyestuffs.
Synthesis Reference(s)Journal of Medicinal Chemistry, 35, p. 734, 1992 DOI: 10.1021/jm00082a014
4-Bromo-2-hydroxybenzaldehyde Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Hydrochloric acid-->Diethyl ether-->Chloroform-->3-Bromophenol
Preparation Products4-Bromo-2-hydroxybenzoic acid-->3-CARBETHOXYUMBELIFERONE

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