ACETYLSALICYLSALICYLIC ACID

ACETYLSALICYLSALICYLIC ACID
  • CAS No.:530-75-6
Other grades of this product :
ACETYLSALICYLSALICYLIC ACID Basic information
Product Name:ACETYLSALICYLSALICYLIC ACID
Synonyms:2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid;SALICYLACETYLSALICYLIC ACID;ACETYLSALICYLSALICYLIC ACID;ACETYLSALISYLIC ACID IMP D;2-HYDROXYBENZOIC ACID ACETATE 2-CARBOXYPHENYL ESTER;o-(o-Acetoxybenzoyloxy)benzoic acid;2-(Ace;Aspirin EP IMpurity D
CAS:530-75-6
MF:C16H12O6
MW:300.26
EINECS:208-493-6
Product Categories:Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:530-75-6.mol
ACETYLSALICYLSALICYLIC ACID Chemical Properties
Melting point 153-160 °C
Boiling point 361.5°C (rough estimate)
density 1.346
refractive index 1.4600 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form neat
pka2.94±0.36(Predicted)
color White to Off-White
Water Solubility 20mg/L(21 ºC)
EPA Substance Registry System2-Carboxyphenyl 2-(acetyloxy)benzoate (530-75-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25
HS Code 29182900
MSDS Information
ProviderLanguage
ACROS English
ACETYLSALICYLSALICYLIC ACID Usage And Synthesis
Chemical Propertieswhite to almost white fine crystalline powder
UsesAntiinflammatory;Cyclooxygenase inhibitor
Usesanalgesic, antipyretic
UsesAcetylsalicylic Acid Impurity C
Purification MethodsCrystallise the analgesic from dilute AcOH or EtOH (m 161-162o), MeOH (m 165-168o), and *C6H6/EtOH (m 163-165o). Its solubilities in boiling Et2O, *C6H6 and EtOH are 1.4%, 2.2% and 33%, respectively. [Baker et al. J Chem Soc 201 1951, Garrett et al. J Am Pharm Soc 48 684 1959, Beilstein 10 I 41, 10 II 54, 10 IV 165.]
ACETYLSALICYLSALICYLIC ACID Preparation Products And Raw materials

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