Other grades of this product :
| Polyhexamethyleneguanidine phosphate Basic information |
| Product Name: | Polyhexamethyleneguanidine phosphate | | Synonyms: | POLYHEXAMETHYLENE GUANIDINE PHOSPHATE;PHMG phosphate;Poly(iminoimidocarbonyliminohexamethylene) phosphate;PHMG phosphate/ Polyhexamethyleneguanidine phosphate;PHMG-P | | CAS: | 89697-78-9 | | MF: | C21H45N9X2.3H3O4P | | MW: | 717.631 | | EINECS: | | Product Categories: | | Mol File: | 89697-78-9.mol |
| Polyhexamethyleneguanidine phosphate Chemical Properties |
| Polyhexamethyleneguanidine phosphate Usage And Synthesis |
| Uses | Polyhexamethyleneguanidine phosphate (PHMG-P) has been widely used as a disinfectant because of its strong bactericidal activity and low toxicity. | | Toxicity evaluation | Administration of PHMG-P induced proinflammatory cytokines elevation and infiltration of immune cells into the lungs. Histopathological analysis revealed a dose-dependent exacerbation of both inflammation and pulmonary fibrosis on day 14. PHMG-P also decreased the total cell number and the CD4+/CD8+ cell ratio in the thymus, with the histopathological examination indicating severe reduction of cortex and medulla. The mRNA levels of biomarkers associated with T cell development also decreased markedly. These findings suggest that exposure of lung tissue to PHMG-P leads to pulmonary inflammation and fibrosis as well as thymic atrophy. |
| Polyhexamethyleneguanidine phosphate Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye