Other grades of this product :
| Lipstatin Basic information |
| Product Name: | Lipstatin | | Synonyms: | N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester;(-)-Lipstatin
N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester;Orlistat Tetradehydro Impurity;Lipstatin;L-Leucine, N-formyl-,(1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-ylester;(2S-(2alpha(1R*,3Z,6Z),3beta))-N-Formyl-L-leucine 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)-3,6-dodecadienyl ester;Lipstatin Solution, 100ppm;[(2S,4E,7E)-1-(3-hexyl-4-oxooxetan-2-yl)trideca-4,7-dien-2-yl] (2S)-2-formamido-3-methylpentanoate | | CAS: | 96829-59-3 | | MF: | C29H49NO5 | | MW: | 491.7 | | EINECS: | 619-246-0 | | Product Categories: | Amino Acids & Derivatives;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 96829-59-3.mol |
| Lipstatin Chemical Properties |
| Boiling point | 627.4±55.0 °C(Predicted) | | density | 0.993 | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 14.57±0.23(Predicted) | | form | Oil | | color | Clear Colorless to Light Yellow |
| Lipstatin Usage And Synthesis |
| Uses | Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases. | | Uses | Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity. |
| Lipstatin Preparation Products And Raw materials |
| Raw materials | 3-Nonene, 1,1-bis(1-methylethoxy)-, (Z)- (9CI)-->5,8-Tetradecadienoic acid, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester, [R-(Z,Z)]- (9CI)-->2-Oxetanone, 3-hexyl-4-(2-hydroxy-4,7-tridecadienyl)-, [3S-[3α,4β(2S*,4Z,7Z)]]- (9CI)-->CIS-3-NONEN-1-OL-->3-nonenal,(Z)-3-nonenal |
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