1,3-Dioxo-2-isoindolineaceticacid

1,3-Dioxo-2-isoindolineaceticacid
  • CAS No.:6296-53-3
Other grades of this product :
1,3-Dioxo-2-isoindolineaceticacid Basic information
Product Name:1,3-Dioxo-2-isoindolineaceticacid
Synonyms:N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide;AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-;3-AcetylaMino-phthalsaeure-anhydrid;3-AcetaMidophthalic anhydride;1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3;3-AcetylaMinophthalic Anhydride;N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide;NSC 16261
CAS:6296-53-3
MF:C10H7NO4
MW:205.17
EINECS:808-040-8
Product Categories:
Mol File:6296-53-3.mol
1,3-Dioxo-2-isoindolineaceticacid Chemical Properties
Melting point 185-186℃
Boiling point 489.1±28.0 °C(Predicted)
density 1.512±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol
form Solid
pka13.81±0.20(Predicted)
color Off-White to Pale Yellow
Stability:Moisture Sensitive
Safety Information
MSDS Information
1,3-Dioxo-2-isoindolineaceticacid Usage And Synthesis
Uses3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2
1,3-Dioxo-2-isoindolineaceticacid Preparation Products And Raw materials
Raw materials3-AMINOPHTHALIC ACID-->3-AMINOPHTHALIC ACID HYDROCHLORIDE

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