2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine

2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
  • CAS No.:161599-46-8
Other grades of this product :

2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Basic information
Product Name:2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
Synonyms:Capecitabine Impurity M;Capecitabine Impurity C (EP );InterMediate of Capecitabine;(2R,3R,4R,5R)-2-(4-aMino-5-fluoro-2-oxopyriMidin-1(2H)-yl)-5-Methyltetrahydrofuran-3,4-diyl diacetate;2',3'-di-O-acetyl-5'-deoxy-5-fulurocytidine;2,3-diACETATE 5,DEOXY 5,FLUORO CYTIDINE;Cytidine,5'-deoxy-5-fluoro-, 2',3'-diacetate;Capecitabine USP IMp.D
CAS:161599-46-8
MF:C13H16FN3O6
MW:329.28
EINECS:605-260-4
Product Categories:Intermediates;Bases & Related Reagents;Nucleotides
Mol File:161599-46-8.mol
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Chemical Properties
Melting point 196-198?C
Boiling point 427.4±55.0 °C(Predicted)
density 1.57±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility soluble in Methanol
form powder to crystal
pka2.49±0.10(Predicted)
color White to Almost white
InChIKeyNWJBWNIUGNXJGO-YHHSPFQVSA-N
CAS DataBase Reference161599-46-8(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
HS Code 29389090
MSDS Information
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesCapecitabine intermediate
UsesA metabolite of Capecitabine.
UsesA metabolite of Capecitabine. Capecitabine Diacetyl Amino Impurity (USP).
DefinitionChEBI: A member of the class of cytidines that is a metabolite of the drug capecitabine.
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Preparation Products And Raw materials
Raw materials4-Pyrimidinamine, 5-fluoro-2-[(trimethylsilyl)oxy]--->D-Ribofuranose, 5-deoxy--->111878-21-8-->Methyl-5-deoxy-2,3-O-isopropylidene-D-ribofuranoside-->5'-Deoxy-5-fluorocytidine-->(3aS,4S,6aR)-4-(iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-->tri-O-acetyl-5-deoxy-D-ribofuranose-->Fluorocytosine-->Acetic anhydride
Preparation Products5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine-->5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine

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