GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
  • CAS No.:7665-99-8
Other grades of this product :
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Basic information
Product Name:GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
Synonyms:Cyclic 3',5'-guanylic acid;Cyclic guanosine phosphate;Guanosine 3',5'-phosphoric acid;Guanosine cyclic 3',5'-monophosphate;3',5'-Cyclic guanosine Monophosphate;3',5'-cGMPH;Guanosine 3′,5′-cyclic monophosphate,cGMP, cyclic GMP;Guanosine 3',5'-Monophosphate
CAS:7665-99-8
MF:C10H12N5O7P
MW:345.21
EINECS:231-641-6
Product Categories:Alphabetic;Analytical Standards;Nucleotides&Nucleosides;Food&Beverage Standards;GChromatography
Mol File:7665-99-8.mol
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties
Melting point >242°C (dec.)
density 2?+-.0.1 g/cm3(Predicted)
storage temp. -20°C
solubility 1% sodium bicarbonate: 50 mg/mL
form powder
pka1.03±0.60(Predicted)
color white
Stability:Hygroscopic
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-26-36
WGK Germany 3
HS Code 29349990
ToxicityThe product formed by the guanylate cyclase enzymes from GTP. It is a cellular “second messenger,” participating in the regulation of many intracellular events. Toxicants (e.g., nitroprusside) may cause physiological changes by interfering with aspects of cyclic GMP metabolism.
MSDS Information
ProviderLanguage
SigmaAldrich English
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis
Chemical PropertiesWhite powder
UsesGuanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation.
DefinitionChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP.
Biochem/physiol ActionsAn important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Preparation Products And Raw materials

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