Product

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE

CAS No.：151266-23-8

Other grades of this product :

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE Basic information

Product Name:	4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE
Synonyms:	3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine;3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE;4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE;4-Amino-3-iodopyrazolo[3,4-d]pyrimidine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-;4-Amino-3-iodo-1H-pyrazolo[3,4-D]pyridine;3-iodo-4-AMino-1H-pyrazolo[3,4-d]pyridine;7-Iodo-7-deaza-8-aza-adenine
CAS:	151266-23-8
MF:	C5H4IN5
MW:	261.02
EINECS:
Product Categories:	Heterocycle-Pyridine series;pharmacetical
Mol File:	151266-23-8.mol

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE Chemical Properties

Boiling point	312.3±52.0 °C(Predicted)
density	2.92±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	10.50±0.20(Predicted)
color	White to Light yellow to Light orange
Sensitive	Light Sensitive
λmax	282nm(lit.)

Safety Information

Hazard Codes	Xn
Risk Statements	36/37/38-22
Safety Statements	26-36/37/39-37
TSCA	N
HS Code	29335990

MSDS Information

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE Usage And Synthesis

Uses

3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.

4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE Preparation Products And Raw materials

Raw materials	4-Chloro-1H-pyrazolo[3,4-d]pyrimidine-->4-Aminopyrazolo[3,4-d]pyrimidine-->2H-Pyrazolo[3,4-d]pyrimidin-4-amine (9CI)-->N-Iodosuccinimide
Preparation Products	(3R)-1-Boc-3-(4-aMino-3-iodo-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873