N,N-Dimethylbenzamide

N,N-Dimethylbenzamide
  • CAS No.:611-74-5
Other grades of this product :
N,N-Dimethylbenzamide Basic information
Product Name:N,N-Dimethylbenzamide
Synonyms:N,N-DiMethylbenzaMide;LABOTEST-BB LT00793055;N,N-DIMETHYLBENZAMIDE;N,N-Dimethylbenzamide;Dimethylbenzamide;Dimethylbenzmide;n,n-dimethyl-benzamid;N,N-Dimethylbenzamide98%
CAS:611-74-5
MF:C9H11NO
MW:149.19
EINECS:210-279-2
Product Categories:AMIDE;Amides;Carbonyl Compounds;Organic Building Blocks
Mol File:611-74-5.mol
N,N-Dimethylbenzamide Chemical Properties
Melting point 43-45 °C (lit.)
Boiling point 132-133 °C/15 mmHg (lit.)
density 1.0753 (rough estimate)
refractive index 1.5279 (estimate)
Fp >230 °F
storage temp. 2-8°C(protect from light)
form powder to lump to clear liquid
pka-1.14±0.70(Predicted)
color White or Colorless to Light yellow
Water Solubility Soluble in water.
BRN 774955
InChIKeyIMNDHOCGZLYMRO-UHFFFAOYSA-N
CAS DataBase Reference611-74-5(CAS DataBase Reference)
NIST Chemistry ReferenceBenzamide, N,N-dimethyl-(611-74-5)
EPA Substance Registry SystemBenzamide, N,N-dimethyl- (611-74-5)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS CV4500000
TSCA Yes
HS Code 29242990
MSDS Information
ProviderLanguage
N,N-Dimethylbenzamide English
SigmaAldrich English
ACROS English
ALFA English
N,N-Dimethylbenzamide Usage And Synthesis
Chemical Propertieswhite to slightly yellow cryst. low melting solid
UsesReagent for deoxygenation of secondary alcohols.
Synthesis Reference(s)The Journal of Organic Chemistry, 36, p. 2721, 1971 DOI: 10.1021/jo00817a036Journal of the American Chemical Society, 77, p. 1114, 1955 DOI: 10.1021/ja01610a010Synthetic Communications, 12, p. 989, 1982 DOI: 10.1080/00397918208061938
General DescriptionN,N-Dimethylbenzamide is a hydrotropic agent and its ability to solubilize drugs with low aqueous solubility has been investigated. It reacts with PhLnI complexes (Ln-Eu, Sm, Yb) to yield benzophenone in good yields. Deuterium exchange labelling experimets on N,N-dimethylbenzamide using [IrH2(Me2CO)2(PPh3)2]BF4 as catalyst and deuterium gas as the source of isotope has been conducted.

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