Product

N-Succinimidyl 6-maleimidohexanoate

CAS No.：55750-63-5

Other grades of this product :

N-Succinimidyl 6-maleimidohexanoate Basic information

Product Name:	N-Succinimidyl 6-maleimidohexanoate
Synonyms:	Mal-heptanoic NHS ester;EMCS N-Succinimidyl 6-maleimidohexanoate;(2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate;6-Maleimidohexanoic acidN-hydroxysuccinimide ester≥ 98% (HPLC);N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE;N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE;N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER;N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE
CAS:	55750-63-5
MF:	C14H16N2O6
MW:	308.29
EINECS:	637-238-5
Product Categories:	Building Blocks;Carbonyl Compounds;N-Substituted Maleimides;Chemical Synthesis;Cyclic Imides;Organic Building Blocks;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Succinimides;i;Heterobifunctional Crosslinker;heteroXlink
Mol File:	55750-63-5.mol

N-Succinimidyl 6-maleimidohexanoate Chemical Properties

Melting point	70-73 °C(lit.)
Boiling point	480.6±47.0 °C(Predicted)
density	1.40±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	chloroform: 100mg/mL
form	powder
pka	-2.21±0.20(Predicted)
color	Off-white to pale brown
Sensitive	Light & Moisture Sensitive & Hygroscopic
BRN	1499815
CAS DataBase Reference	55750-63-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	36/37/38-40
Safety Statements	26-36/37-36
WGK Germany	3
F	8-10-21
HS Code	29280000

MSDS Information

Provider	Language
SigmaAldrich	English

N-Succinimidyl 6-maleimidohexanoate Usage And Synthesis

Description	Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Chemical Properties	White to cream colored crystals
Uses	6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in: Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction. Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent. Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

N-Succinimidyl 6-maleimidohexanoate Preparation Products And Raw materials

Raw materials	6-Maleimidocaproic acid-->(Z)-6-(3-Carboxyacrylamido)hexanoic acid-->5-AMINOVALERIC ACID-->N-Hydroxysuccinimide-->6-Aminocaproic acid
Preparation Products	MC-Val-Cit-PAB-->L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873