Biotin-PEG4-N3

Biotin-PEG4-N3
  • CAS No.:875770-34-6
Other grades of this product :
Biotin-PEG4-N3 Basic information
Product Name:Biotin-PEG4-N3
Synonyms:Biotin-PEG4-N3;1H-Thieno[3,4-d]imidazole-4-pentanamide,N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-,(3aS,4S,6aR)-;Biotin-PEG4-azide;N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]biotinaMide;(+)-Biotin-PEG4-CH2CH2azide;(3aS,4S,6aR)-N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;Azide-PEG3-biotin conjugate;(+)-BIOTIN-PEG4-AZIDE
CAS:875770-34-6
MF:C18H32N6O5S
MW:444.55
EINECS:
Product Categories:SiChem;peg
Mol File:875770-34-6.mol
Biotin-PEG4-N3 Chemical Properties
Melting point 107.0 to 112.0 °C
storage temp. -20°C
form Solid
color Off-white to Gray
Water Solubility Solubile in DMSO, DMF and water.
Safety Information
WGK Germany 3
MSDS Information
Biotin-PEG4-N3 Usage And Synthesis
DescriptionBiotin-PEG3-azide is a PEGylated version of biotin-azide that is more hydrophilic due to the incorporation of a PEGylated spacer. It can be used to label terminal alkynes via copper-catalyzed click reactions or copper-free click reactions with cyclooctynes., Biotin-PEG3-azide has been used to non-enzymatically and covalently tag proteins, which can be separated and detected using common laboratory methods such as SDS-PAGE and Western blot. It can be used in combination with other protein tags. Biotin-PEG3-azide has also been used in nanostructured biointerfaces to study ligand and receptor spacing when there are different signaling molecules present.
UsesBiotinylation reagent for labeling alkyne containing molecules or biomolecules using either copper-catalyzed 1,3 dipolar cycloaddition click chemistry or copper-free click chemistry with cyclooctyne derivatives. The azide group reacts with alkynes to form a stable triazole linkage facilitating the introduction of biotin into your alkyne modified system of interest. This reaction is bioorthogonal or in other words compatible with biological systems in that it?s components do not react with the biological environment.
Biotin-PEG4-N3 Preparation Products And Raw materials
Preparation ProductsN-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE

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