| 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Basic information |
| Product Name: | 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one |
| Synonyms: | 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one;Eltrombopag Impurity 35;2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one;2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one;Eltrombopag Intermediate 1;EltroMbopag II;2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine;1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol |
| CAS: | 277299-70-4 |
| MF: | C12H14N2O |
| MW: | 202.25 |
| EINECS: | 1592732-453-0 |
| Product Categories: | |
| Mol File: | 277299-70-4.mol |
| 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Chemical Properties |
| Melting point | 121.0 to 125.0 °C |
| Boiling point | 338.5±52.0 °C(Predicted) |
| density | 1.121 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 0.79±0.40(Predicted) |
| color | Pale Beige to Light Beige |
| Safety Information |
| MSDS Information |
| 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Usage And Synthesis |
| Uses | 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia. |
| 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Preparation Products And Raw materials |
| Raw materials | 3,4-Dimethylphenylhydrazine hydrochloride-->Ethyl acetoacetate |
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