| Isoquinoline, 1,7-dichloro-4-Methoxy- Basic information |
| Product Name: | Isoquinoline, 1,7-dichloro-4-Methoxy- |
| Synonyms: | 1,7-dichloro-4-Methoxyisoquinoline;Isoquinoline, 1,7-dichloro-4-Methoxy-;Asunaprevir Intermediate 2;Asunaprevir N-1;630423-36-8 |
| CAS: | 630423-36-8 |
| MF: | C10H7Cl2NO |
| MW: | 228.07 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 630423-36-8.mol |
| Isoquinoline, 1,7-dichloro-4-Methoxy- Chemical Properties |
| Melting point | 137.0 to 142.0 °C |
| Boiling point | 355.7±37.0 °C(Predicted) |
| density | 1.384±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | 0.98±0.34(Predicted) |
| color | White to Yellow to Orange |
| Safety Information |
| MSDS Information |
| Isoquinoline, 1,7-dichloro-4-Methoxy- Usage And Synthesis |
| Uses | 1,7-Dichloro-4-methoxyisoquinoline acts as a reagent in the synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease. Preparation, SAR of methoxyisoquinoline derivatives and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. |
| Isoquinoline, 1,7-dichloro-4-Methoxy- Preparation Products And Raw materials |
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