Other grades of this product :
| Thiazolidine-4-carboxylic acid Basic information |
| Thiazolidine-4-carboxylic acid Chemical Properties |
| RIDADR | 2811 | | HazardClass | 6.1(b) | | PackingGroup | III |
| Thiazolidine-4-carboxylic acid Usage And Synthesis |
| Originator | Hepaldine,Riker,France,1964 | | Uses | hepatoprotectant | | Uses | Timonacic is a derivative of Proline (P756050), a cyclic nonessential amino acid. Timonacic is a research molecule of interest with potential antineoplastic activities by acting on the cell membrane of tumour cells and causing reverse transformation to normal cells. | | Definition | ChEBI: A sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom. | | Manufacturing Process | Cysteine is first dissolved in distilled water which has been freed of oxygen by
boiling. Formaldehyde of 30% (w/v) concentration is added while stirring and
the temperature of the mixture rises, while the thiazolidine carboxylic acid
begins crystallizing. The stirring is continued for 2 hours after which ethyl
alcohol of 95% (w/v) concentration is added to induce further crystallization.
The mixture is left to stand for 24 hours at 4°C. The mixture is then filtered
with retention of a crude product, which is purified by recrystallization from
boiling distilled water. The crystals are then dried at about 40°C. The free acid
is then converted to the sodium salt with NaOH. | | Therapeutic Function | Hepatoprotectant, Choleretic |
| Thiazolidine-4-carboxylic acid Preparation Products And Raw materials |
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