2-Chloropropionitrile

2-Chloropropionitrile
  • CAS No.:1617-17-0
Other grades of this product :
2-Chloropropionitrile Basic information
Product Name:2-Chloropropionitrile
Synonyms:2-Chloropropanenitrile;Propanenitrile, 2-chloro-;2-CHLOROPROPIONITRILE;2-Chloropropionitrile 95%;(2S)-2-chloropropanenitrile;(2S)-2-chloropropionitrile;2-chlorpropionitrile;oropropionitriL
CAS:1617-17-0
MF:C3H4ClN
MW:89.52
EINECS:216-570-0
Product Categories:C1 to C5;Cyanides/Nitriles;Nitrogen Compounds
Mol File:1617-17-0.mol
2-Chloropropionitrile Chemical Properties
Melting point 54-55 °C
Boiling point 120-122 °C (lit.)
density 1.012 g/mL at 25 °C (lit.)
refractive index n20/D 1.413(lit.)
Fp 92 °F
storage temp. Sealed in dry,Room Temperature
NIST Chemistry ReferenceCH3CHClCN(1617-17-0)
Safety Information
Hazard Codes T
Risk Statements 10-23/24/25-36/37/38
Safety Statements 16-26-27-36/37/39-45
RIDADR UN 3275 6.1/PG 2
WGK Germany 3
HazardClass 3.2
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Chloropropionitrile Usage And Synthesis
Description2-Chloropropionitrile (2-CPN) is a colorless flammable liquid with a characteristic acrid odor.
UsesMajor uses of this chemical are in pharmaceutics and polymer synthesis.
Uses2-Chloropropionitrile was used as initiator during the single-pot atom-transfer radical polymerization under microwave irradiation for the synthesis of polyacrylonitrile. It was used in the synthesis of:
  • nitrile functionalized methimazole-based ionic liquids
  • (+)- and (-)-anatoxin
Environmental FateMost of the toxicity of propionitrile results from release of cyanide. Cause of death is due to lack of oxygen to the body’s cells, especially to the brain and heart cells.
Acquired resistanceAccording to Henry’s law constant of 1.43×10-5 atmm3 mol-1, vapor pressure of 2.770mmHg and water solubility of 45 g ml-1 at 25°C are expected to indicate that volatilization from moist soil and water surfaces is expected to be an important fate process and also it can be volatilized from dry soil surfaces and exist as a vapor in the atmosphere.When heated to decomposition, it emits very toxic fumes of chlorine-containing compounds: nitrogen oxides, hydrogen cyanide, and hydrogen chloride.
2-Chloropropionitrile Preparation Products And Raw materials
Preparation Products3,5,6-Trichloro-2-pyridinol

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