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| PEG7-t-butly ester Basic information |
| Product Name: | PEG7-t-butly ester | | Synonyms: | PEG7-t-butly ester;Hydroxy-PEG6-t-butly ester;Hydroxy-PEG6-t-butyl ester;HO-PEG6-CH2CH2COOtBu;OH-PEG6-CH2CH2COOtBu;OH-PEG6-TBA;HO-PEG4-t-Butyl ester;Hydroxy-PEG6-t-butyl ester 96% | | CAS: | 361189-64-2 | | MF: | C19H38O9 | | MW: | 410.5 | | EINECS: | | Product Categories: | peg | | Mol File: | 361189-64-2.mol |
| PEG7-t-butly ester Chemical Properties |
| Boiling point | 481.8±40.0 °C(Predicted) | | density | 1.076±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 14.36±0.10(Predicted) |
| PEG7-t-butly ester Usage And Synthesis |
| Description | Hydroxy-PEG6-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. | | Uses | This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation. |
| PEG7-t-butly ester Preparation Products And Raw materials |
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