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| Tetrazine-PEG5-NHS ester Basic information |
| Product Name: | Tetrazine-PEG5-NHS ester | | Synonyms: | Tetrazine-PEG5-NHS ester;Tetrazine-PEG5-NHS ester >=95%;Tetrazine-Ph-PEG5-NHS ester;4,7,10,13,16-Pentaoxa-20-azaheneicosanoic acid, 19-oxo-21-[4-(1,2,4,5-tetrazin-3-yl)phenyl]-, 2,5-dioxo-1-pyrrolidinyl ester | | CAS: | 1682653-80-0 | | MF: | C27H36N6O10 | | MW: | 604.61 | | EINECS: | | Product Categories: | | Mol File: | 1682653-80-0.mol |
| Tetrazine-PEG5-NHS ester Chemical Properties |
| storage temp. | -20°C | | form | powder or crystals |
| Tetrazine-PEG5-NHS ester Usage And Synthesis |
| Description | Tetrazine-PEG5-NHS Ester is a PEG linker containing a tetrazine group and an NHS ester which is very reactive with amine(NH2)-containing molecule. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene). | | Uses | Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction. | | General Description | Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm. |
| Tetrazine-PEG5-NHS ester Preparation Products And Raw materials |
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