2-Morpholinoethyl isocyanide

CAS No.：78375-48-1

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Morpholinoethyl isocyanide Basic information

Product Name:	2-Morpholinoethyl isocyanide
Synonyms:	Morpholino ethyl isocyanide;Morpholine, 4-(2-isocyanoethyl)-;MEI 2-MORPHOLINOETHYL ISOCYANIDE;Morpholinyl-4-ethylisocyanid-2;4-(2-Isocyanatoethyl)morpholine;2-Morpholinoethyl is;2-Morpholinoethyl isocyanide >=98.0% (GC);MEI
CAS:	78375-48-1
MF:	C7H12N2O
MW:	140.19
EINECS:
Product Categories:	Nitro / Nitriles
Mol File:	78375-48-1.mol

2-Morpholinoethyl isocyanide Chemical Properties

Boiling point	72-73 °C0.7 mm Hg(lit.)
density	1.017 g/mL at 20 °C(lit.)
refractive index	n20/D 1.469
Fp	110 ºC
storage temp.	-20°C
BRN	4666990
CAS DataBase Reference	78375-48-1(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	23/24/25-36/37/38
Safety Statements	26-36/37-45
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
F	10-21
HazardClass	6.1(b)
PackingGroup	III

MSDS Information

Provider	Language
SigmaAldrich	English

2-Morpholinoethyl isocyanide Usage And Synthesis

Uses

2-Morpholinoethyl isocyanide can be used for the synthesis of:

Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes.
Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction.
2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities.

It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).

2-Morpholinoethyl isocyanide Preparation Products And Raw materials

Raw materials

Formamide, N-[2-(4-morpholinyl)ethyl]-

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