Cyclobutyl chloride

CAS No.：1120-57-6

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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Cyclobutyl chloride Basic information

Product Name:	Cyclobutyl chloride
Synonyms:	CYCLOBUTYL CHLORIDE;CHLOROCYCLOBUTANE;1-Chlorocyclobutane;Cyclobutyl chloride,97%;CHLOROCYCLOBUTANE,CYCLOBUTYL CHLORIDE;Chlorocyclobutane, 97+%;Chlorocyclobutane >Cyclobutane, chloro-
CAS:	1120-57-6
MF:	C4H7Cl
MW:	90.55
EINECS:	214-314-2
Product Categories:	Halogenated Hydrocarbons;Organic Building Blocks;API intermediates;Cyclobutanes & Cyclobutenes;Simple 4-Membered Ring Compounds;Alkyl;Building Blocks;Chemical Synthesis
Mol File:	1120-57-6.mol

Cyclobutyl chloride Chemical Properties

Melting point	155-156 °C
Boiling point	83 °C (lit.)
density	0.991 g/mL at 25 °C (lit.)
refractive index	n20/D 1.436(lit.)
Fp	16 °F
storage temp.	2-8°C
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	0.991
Water Solubility	Insoluble in water.
BRN	1900414
CAS DataBase Reference	1120-57-6(CAS DataBase Reference)
NIST Chemistry Reference	Chlorocyclobutane(1120-57-6)

Safety Information

Hazard Codes	F,Xn
Risk Statements	11-20/21/22
Safety Statements	16-33-36/37/39
RIDADR	UN 1993 3/PG 2
WGK Germany	3
HazardClass	3
PackingGroup	II
HS Code	29038900

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

Cyclobutyl chloride Usage And Synthesis

Chemical Properties	clear colorless liquid
Uses	It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuffs.
Synthesis Reference(s)	Synthetic Communications, 20, p. 1011, 1990 DOI: 10.1080/00397919008052804
General Description	Cyclobutyl chloride is formed by rearrangements concerted with fragmentation of cyclopropylmethoxychlorocarbene and cyclobutoxychlorocarbene. The thermal decomposition of cyclobutyl chloride was investigated over the temperature range of 892-1150K using very low-pressure pyrolysis technique.

Cyclobutyl chloride Preparation Products And Raw materials

Raw materials	Bicyclo[1,1,0]butane-->3H-Diazirine, 3-chloro-3-(cyclopropylmethoxy)--->Cyclopropylmethyl ethyl ether-->Cyclobutanol-->CYCLOBUTANE
Preparation Products	4-CHLORO-1-BUTENE

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