Other grades of this product :
| Oxazole Chemical Properties |
| Melting point | −87-−84 °C(lit.) | | Boiling point | 69-70 °C(lit.) | | density | 1.05 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.425(lit.) | | Fp | 66 °F | | storage temp. | Sealed in dry,2-8°C | | pka | 0.8(at 33℃) | | form | clear liquid | | color | Colorless to Almost colorless | | Water Solubility | Miscible with alcohol and ether. Slightly miscible with water. | | BRN | 103851 | | CAS DataBase Reference | 288-42-6(CAS DataBase Reference) | | NIST Chemistry Reference | Oxazole(288-42-6) |
| Oxazole Usage And Synthesis |
| Description | Oxazole is the primary compound for a various class of heterocyclic aromatic organic compounds, which include azoles with a nitrogen and an oxygen separated by one carbon. Oxazole is a weak base and an aromatic compound.
| | Preparation | There are various methods of synthesizing oxazole in organic chemistry including Van Leusen reaction with TosMIC and aldehydes, Robinson-Gabriel preparation by dehydration of 2-acylaminoketones, and Bredereck reaction with formamide. Oxazole result from the oxidation and cyclization of threonine and serine non-ribosomal peptides.
| | Chemical Properties | Colorlesstolightyellowliqui | | Uses | Oxazole and its derivatives are actively involved as building blocks for bio chemicals and pharmaceuticals like flopristin and darglitazone. It is also involved in industrial applications such as in dyes, fluorescent brightening agents, textile auxiliaries and plastics. | | Definition | ChEBI: A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3. | | Definition | oxazole: A heterocyclic compoundhaving a nitrogen atom and an oxygenatom in a five-membered ring,C3H3NO. | | General Description | Oxazole ring is present in various natural products. The diradical interactions in the ring-opening reaction of oxazole were studied. |
| Oxazole Preparation Products And Raw materials |
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