MES sodium salt

MES sodium salt
  • CAS No.:71119-23-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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MES sodium salt Basic information
Product Name:MES sodium salt
Synonyms:Natrium-4-morpholin-1-ylethylsulfonat;2-(N-Morpholino)ethanesulphonic acid sodium salt;4-Morpholine-1-ethanesulfonic acid sodium salt;MES sodium salt,99%;2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt;4-Morpholineethanesulfonic acid, sodium salt (1:1);Einecs 275-203-2;MES sodium salt,2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt
CAS:71119-23-8
MF:C6H12NNaO4S
MW:217.22
EINECS:275-203-2
Product Categories:Pharmaceutical Raw Materials
Mol File:71119-23-8.mol
MES sodium salt Chemical Properties
Melting point >250?C (dec.)
density 1.507[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. room temp
solubility H2O: 0.5 g/mL, clear, colorless
form Powder
color White
PH Range5.5 - 6.7
Water Solubility 335.3g/L at 20℃
BRN 3765682
LogP-2.36 at 20℃
CAS DataBase Reference71119-23-8(CAS DataBase Reference)
EPA Substance Registry System4-Morpholineethanesulfonic acid, sodium salt (71119-23-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 1
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
MES sodium salt Usage And Synthesis
Chemical PropertiesWhite powder
UsesMES sodium salt is a buffering agent used in biological and biochemical research including plant cell culture. It has been used:To achieve the required density and stretching of DNA fibers during melting of agarose plugs containing genomic DNA.To equilibrate the Balch homogenizer chamber and to prevent sample hydrolysis before sample homogenization.
UsesMES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.
DefinitionChEBI: Sodium 2-(N-morpholino)ethanesulfonate is the organic sodium salt that is the sodium salt of 2-(N-morpholino)ethanesulfonic acid. It contains a 2-(N-morpholino)ethanesulfonate.
General DescriptionMES is one of the so-called "Good" buffers developed for biological applications. This product is BioPerformance certified (suitable for electrophoresis, tissue culture, and molecular biology applications. A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa=±1). Alternatively, volumes of equimolar solutions of MES free acid and MES sodium can be mixed to attain the desired pH. Standard mixing tables using stock solutions to prepare a buffer of a given pH have been published.
Flammability and ExplosibilityNotclassified
MES sodium salt Preparation Products And Raw materials

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