1-Benzyl-3-pyrrolidinone

1-Benzyl-3-pyrrolidinone
  • CAS No.:775-16-6
Other grades of this product :
1-Benzyl-3-pyrrolidinone Basic information
Product Name:1-Benzyl-3-pyrrolidinone
Synonyms:1-BENZYL-3-PYRROLIDINONE;1-BENZYL-3-PYRROLIDONE;1-BENZYLPYRROLIDIN-3-ONE;N-BENZYL-3-PYRROLIDONE;1-(PHENYLMETHYL)-3-PYRROLIDINONE;N-BeNzyl-3-pyrrolidiNoNe;5 N-Benzyl-3-Pyrrolidone;1-BENZLY-3-PYRROLIDONE
CAS:775-16-6
MF:C11H13NO
MW:175.23
EINECS:212-274-0
Product Categories:Building Blocks;C11 to C12;Pyrrole&Pyrrolidine&Pyrroline;Pharmaceutical Intermediates;Chemical Synthesis;Heterocyclic Building Blocks;Amines and Anilines;Carbonyl Compounds;Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
Mol File:775-16-6.mol
1-Benzyl-3-pyrrolidinone Chemical Properties
Boiling point 77 °C/0.01 mmHg (lit.)
density 1.091 g/mL at 25 °C (lit.)
refractive index n20/D 1.539(lit.)
Fp >230 °F
storage temp. 2-8°C
form Crystalline Powder, Crystals or Chunks
pka5.56±0.20(Predicted)
color White to off-white
BRN 1526217
CAS DataBase Reference775-16-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 26-37/39-24/25-36
WGK Germany 3
10
HazardClass IRRITANT, KEEP COLD
HS Code 29339900
MSDS Information
ProviderLanguage
1-(Phenylmethyl)-3-pyrrolidinone English
ACROS English
SigmaAldrich English
ALFA English
1-Benzyl-3-pyrrolidinone Usage And Synthesis
Chemical Propertiesclear yellow liquid
UsesSubstrate used to prepare chiral, alkenyl sulfoximines leading to highly functionalized diazabicycles.1
Uses1-Benzyl-3-pyrrolidinone is a substrate used to prepare chiral, alkenyl sulfoximines leading to highly functionalized diazabicycles.
Uses1-Benzyl-3-pyrrolidinone was used as starting reagent in the synthesis of vinyl triflate. It was used to prepare chiral, alkenyl sulfoximines leading to highly functionalized diazabicycles.
General DescriptionThe equilibrium constant for the ketoreductase-catalyzed reduction reaction of 1-benzyl-3-pyrrolidinone has been measured in n-hexane. 1-Benzyl-3-pyrrolidinone on enzymatic asymmetric reduction yields enantiopure 1-benzyl-3-hydroxypyrrolidine, well known intermediate for various drugs.
1-Benzyl-3-pyrrolidinone Preparation Products And Raw materials
Raw materialsMethanol, 1-(tributylstannyl)-, 1-methanesulfonate-->3-Pyrrolidinone-->1-BROMOBUT-3-EN-2-ONE-->N-Benzyl-3-pyrrolidinol-->Benzyl alcohol-->Benzylamine
Preparation Products(S)-1-Benzyl-3-pyrrolidinol

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