Dimethyldioctadecylammonium bromide

CAS No.：3700-67-2

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Dimethyldioctadecylammonium bromide Basic information

Product Name:	Dimethyldioctadecylammonium bromide
Synonyms:	DiMethyldioctadecylaMMoniuM (BroMide Salt);DIMETHYLDIOCTADECYLAMMONIUM (BROMIDE SALT);18:0 DDAB;DDA;DIMETHYLDIOCTADECYLAMMONIUM BROMIDE;DIMETHYL DI-N-OCTADECYLAMMONIUM BROMIDE;DIMETHYLDISTEARYLAMMONIUM BROMIDE;DISTEARYLDIMETHYLAMMONIUM BROMIDE;18:0 DDAB
CAS:	3700-67-2
MF:	C38H80BrN
MW:	630.95
EINECS:	223-037-6
Product Categories:	Ammonium Bromides (Quaternary);Quaternary Ammonium Compounds
Mol File:	3700-67-2.mol

Dimethyldioctadecylammonium bromide Chemical Properties

Melting point	~160 °C
density	1.047
RTECS	RG0185984
refractive index	1.5260 (estimate)
storage temp.	-20°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Hexanes (Slightly, Heat
form	Granular Powder
color	White
BRN	3580323
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	3700-67-2(CAS DataBase Reference)
EPA Substance Registry System	1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide (3700-67-2)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-43
Safety Statements	26-37/39
WGK Germany	3
TSCA	Yes
HazardClass	9
HS Code	29211990

MSDS Information

Provider	Language
DDAB	English
ACROS	English
SigmaAldrich	English
ALFA	English

Dimethyldioctadecylammonium bromide Usage And Synthesis

Description	18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion.
Chemical Properties	white powder
Uses	Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV).
General Description	18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids.
Biochem/physiol Actions	18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic.
Purification Methods	Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.]

Dimethyldioctadecylammonium bromide Preparation Products And Raw materials

Raw materials

Dimethylamine-->1-Bromooctadecane

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