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| 5-Hydroxyindole-2-carboxylic acid Basic information |
| 5-Hydroxyindole-2-carboxylic acid Chemical Properties |
| Melting point | 249 °C (dec.) (lit.) | | Boiling point | 309.06°C (rough estimate) | | density | 1.3312 (rough estimate) | | refractive index | 1.5200 (estimate) | | storage temp. | Sealed in dry,2-8°C | | solubility | chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown | | form | Fuming Liquid | | pka | 4.38±0.30(Predicted) | | color | Clear colorless to slightly yellow | | BRN | 153214 | | CAS DataBase Reference | 21598-06-1(CAS DataBase Reference) |
| 5-Hydroxyindole-2-carboxylic acid Usage And Synthesis |
| Chemical Properties | light yellow to beige crystalline powder | | Uses | • ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal | | Uses | A competitive antagonist of potentiation by glycine at the N-methyl-D-aspartate receptors that have been linked to neuronal death, assiciated to such afflictions as stroke and epilepsy. | | Uses | 5-Hydroxyindole-2-carboxylic acid was used in HPLC-amperometric detection of serotonin in plasma, platelets and urine. | | General Description | 5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid. |
| 5-Hydroxyindole-2-carboxylic acid Preparation Products And Raw materials |
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