| Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate Basic information |
| Product Name: | Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate |
| Synonyms: | Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate;ETHYL 2-(3-CYANO-4-HYDROXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE;2-(3-Cyano-4-hydroxyphenyl)-4-Methyl-1,3-thiazole-5-carboxylicacidethylester;Febuxostat Impurity 5;2-(3-Cyano-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid ethyl ester;Febuxostat 4-Hydroxy Ethyl Ester;Ethyl 2-(3-cyano-4-hydroxyphenyl);FeBuxostat Impurity 28 |
| CAS: | 161798-02-3 |
| MF: | C14H12N2O3S |
| MW: | 288.32 |
| EINECS: | 1308068-626-2 |
| Product Categories: | Febuxostat intermediate;Pharmaceutical Intermediates |
| Mol File: | 161798-02-3.mol |
| Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate Chemical Properties |
| Melting point | 208 - 210oC |
| Boiling point | 475.3±55.0 °C(Predicted) |
| density | 1.38 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 5.80±0.20(Predicted) |
| form | Solid |
| color | Off-White |
| Safety Information |
| MSDS Information |
| Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate Usage And Synthesis |
| Uses | 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester, can be used for the synthesis of Febuxostat (F229000), an antipodagrics. |
| Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate Preparation Products And Raw materials |
| Preparation Products | Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate |
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