Acetylene-PEG5-acid

Acetylene-PEG5-acid
  • CAS No.:1245823-51-1
Other grades of this product :
Acetylene-PEG5-acid Basic information
Product Name:Acetylene-PEG5-acid
Synonyms:Propyne-PEG4-CH2CH2COOH;Alkyne-PEG4-Acid;Alkyne-PEG5-COOH;PROPARGYL-PEG5-COOH;Propargyl-PEG4-CH2CH2COOH;Acetylene-PEG5-acid;Alkyne-PEG5-acid;Propargyl-PEG5-acid
CAS:1245823-51-1
MF:C14H24O7
MW:304.34
EINECS:
Product Categories:peg
Mol File:1245823-51-1.mol
Acetylene-PEG5-acid Chemical Properties
Boiling point 426.3±45.0 °C(Predicted)
density 1.127±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in Water, DMSO, DCM, DMF
pka4.28±0.10(Predicted)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
WGK Germany 3
MSDS Information
Acetylene-PEG5-acid Usage And Synthesis
DescriptionPropargyl-PEG5-acid has a propargyl group at one end and an acid group at the other end. The acid can react with primary amines to form a stable amide bond, activation will be needed. The PEG units enhances solubility of the molecule in aqueous environment. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
UsesPropargyl-peg5 Acid is used as a reactant in the preparation of site-specific antibody-pyrrolobenzodiazepine conjugates.
UsesAlkyne-PEG5-acid may be used in the synthesis of peptide nucleic acid (PNA) oligomers that can conjugate with vitamin B12 via Cu-catalyzed 1,3-dipolar cycloaddition in order to study if vitamin B12 to transport PNA oligonucleotides into bacterial cells.
Acetylene-PEG5-acid Preparation Products And Raw materials

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